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Sickle Cell Anemia - Contraindications

NONINDICATIONS AND CONTRAINDICATIONS The following are not considered appropriate indications for transfusion, and transfusion is not recommended in these clinical settings:

  • Chronic steadystate anemia. Most patients with sickle cell disease are relatively asymptomatic from their anemia and do not require transfusions to improve oxygencarrying capacity.

  • Uncomplicated acute painful crises.

  • Infections.

  • Minor surgery not requiring prolonged general anesthesia (e.g., myringotomy, simple biopsy).

  • Aseptic necrosis of the hip or shoulder (except when surgery is required).

  • Uncomplicated pregnancy.
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